Isana Deva (or Mahadeva) is also one of the eight deities of the directions. Isana Deva word Isana represents the north-east corner. Isana Deva resides in the north-east direction. Isana Deva is seated on a chariot drawn by bulls. He is white in colour and holds in his two hands a trident and a kapala. A half moon appears on his matted hair. He is adorned with a sacred thread of a serpent and his body is besmeared with ashes. His throat appears blue. He is naked and has three eyes.

In the Durgatiparisodhana Tantra, the Lord of the all the spirits bowed before the Lord Buddha and said, “O Lord with regard to that king, prince warrior or brahman, I will guarantee refuge here and beyond, provide protection, tranquility and happiness, immunity to the sword and punishment counteracting and destroying poison, stability of borders, regions and estates. I will provide them with a Vajra enclosure made of Vajra darts, and a Vajra Canopy. I will assist them in needs and give an indication of what is to be done and what not. I will explain through a dream that is auspicious and inauspicious. I will help for every success with no obstruction to the performers of rites.”

As usual he is also worshipped in the Guru mandala rite of Nepalese Buddhist tradition, in a group of eight deities of directions.